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diagnosis rheumatology allergy differential hypersensitivity reactions vasculitis champs cryoglobulinemia cryoglobulins druginduced hematology low management mnemonic pathophysiology sle vasculitides
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... 1 (50%-80%), type ... glomerulonephritis (>90%) S - Systemic ... Lupus Erythematosus ... #Low #Complement
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Allergen-specific lgE causes ... glomerulonephritis, Systemic ... lupus erythematosus ... #classification ... #comparison
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
- Local and systemic ... Complement activation ... lupus erythematosus ... #Classification ... Diagnosis #Reactions #Table
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
90% - Low complement ... Discontinuation of causal ... months to years) Systemic ... #sle #comparison ... #table #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... • Low serum C4 complement ... lupus erythematosus ... #classification
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... inflammation Others: • Lupus ... lupus erythematosus ... against MPO • Complement ... #rheumatology #classification
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