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diagnosis rheumatology differential anca cryoglobulins cutaneous ddxof dermatology erythematosus im lupus management medium rheum size sjogrens skin syndrome systemic types
A System for Vasculitides #Diagnosis #IM #Rheum #Vasculitis #Small #Medium #Large #Vessel #Size #Classification #ANCA #Differential
A System for Vasculitides ... #Small #Medium ... #Large #Vessel # ... Size #Classification ... #Differential #Algorithm
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
abnormalities SMALL ... , arthritis LARGE ... against MPO • Complement ... , and SLE) • Urinalysis ... #rheumatology #classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
diseases: - 10% SLE ... • Low serum C4 complement ... • Cutaneous small-vessel ... erythematosus (SLE ... diagnosis #types #classification
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Secondary: CTD: SLE ... Findings: • Small ... ulceration Small ... Urticarial/LCV) - Cryoglobulinemic ... Polyarteritis nodosa Large
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
diseases, such as SLE ... discrepancies LARGE ... and infarcts SMALL ... / ANCA + MPO) Cryoglobulinemic ... ) • Hypocomplementemic
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Skin Disease Classification ... inflammation of the small ... and large bowel ... RNP antibodies, Complement
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Cytopenia: 2% • Hypocomplementemia ... nervous system: small-fiber ... : • 7%, Cryoglobulinemia ... cell lymphoma • Large
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