7 results
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
table of types of hypersensitivity ... antigens, leading to complement ... they activate complement ... allergy #table #classification ... #comparison
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Hypersensitivity ... antigen, leading to complement ... Complement activation ... sclerosis #Hypersensitivity ... #Types #Classification
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... #rheumatology #classification
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Low serum C4 complement ... vasculitis • Hypersensitivity ... diagnosis #types #classification
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
90% - Low complement ... 80% - Low complement ... Usual therapeutic management ... druginduced #lupus #sle #comparison ... rheumatology #diagnosis #management
IGG-4 RELATED DISEASE

WHAT?
 • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
- ↑ IgE, ↓ complement ... • Classification ... mimics excluded MANAGEMENT ... IGG4 #Diagnosis #Management
Diets and Inflammatory Bowel Disease (IBD)
Diet affects IBD by 3 mechanisms
1. Microbiome ( ↓ diversity)
2. Mucosal
• Nutrition as complement ... IBD #Nutrition #comparison ... #table #management