10 results
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Immunological Target: Allergen ... peanuts), Hay fever ... , Urticaria, Allergic ... #Allergic #Reactions ... #Types #Classification
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
Soluble antigen - Allergen-specific ... When the specific allergen ... , seasonal hay fever ... Pathophysiology #Allergy ... #Diagnosis #Reactions
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Mechanism of Action: Allergen-specific ... Anaphylaxis, Hay fever ... they activate complement ... reactions #types #allergy ... #table #classification
Complement 1 esterase inhibitor (C1-INH) Deficiency Testing Algorithm
INDICATIONS FOR TESTING:
 • Recurrent angioedema (without urticaria)
 •
Complement 1 esterase ... Deficiency Testing Algorithm ... ARUPLabs #C1INH #Complement ... Deficiency #Testing #Algorithm ... #allergy #diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Urticaria and hypocomplementemia ... Coronary arteries - Fever ... Vasculitis: • Fevers ... against MPO • Complement ... #rheumatology #classification
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
permanent organ dysfunction ... Actively maintained fever ... transfusion • Allergic ... Anesthesia #Checklist #Diagnosis
Anosmia / Smell Dysfunction - Differential Diagnosis Algorithm
Nasal Obstruction/ URTI:
 • Septal Deviation
 • Allergic Rhinitis
Anosmia / Smell Dysfunction ... - Differential Diagnosis ... Algorithm Nasal ... Deviation • Allergic ... #Algorithm #Causes
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm
Structural Defect - Asplenia/HypospIenism
 • Bacteremia/Septic
Causes of Fever ... - Differential Diagnosis ... Algorithm Structural ... or Neutrophil Dysfunction ... Periodontal Disease Complement
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... anti-Smith Ab, low complements ... Skin Disease Classification ... Differential Diagnosis ... mild cognitive dysfunction
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
or family - Ever ... difficult airway - Allergies ... event, follow ACC algorithm ... or LV dysfunction ... stratification #diagnosis