14 results
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... Systemic Lupus Erythematosus ... @AnnKumfer #Hypocomplementemia ... #Low #Complement ... Mnemonic #diagnosis #differential
Lumbar stenosis guide we created to implement consistent radiology reporting across our multi-hospital network. 
Lumbar Central
we created to implement ... Lumbar Central Canal ... Stenosis Grading ... #Classification ... #Central #Foraminal
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
ischemia - Skin: erythematous ... gastrointestinal, and/or central ... systemic lupus erythematosus ... against MPO • Complement ... #rheumatology #classification
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
cellular antigen, leading ... to complement activation ... Complement activation ... systemic lupus erythematosus ... Hypersensitivity #Types #Classification
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Skin Disease Classification ... permanent alopecia Differential ... mild cognitive dysfunction ... RNP antibodies, Complement
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
cell antigens, leading ... to complement activation ... they activate complement ... Systemic lupus erythematosus ... allergy #table #classification
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
immune system, leading ... • Low serum C4 complement ... systemic lupus erythematosus ... diagnosis #types #classification
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
IL-1 and IL-6, leading ... Systemic lupus erythematosus ... lymphadenopathy • Central ... nervous system (CNS) dysfunction ... systemic lupus erythematosus
Shock Types - Classification
State of cellular and tissue hypoxia due to: reduced oxygen delivery, increased oxygen
Shock Types - Classification ... END-ORGAN DYSFUNCTION ... Hemorrhagic → leading ... water #Shock #Classification ... #criticalcare #differential
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... ischemia • Skin: Erythematous ... Angiitis of the Central ... Vasculitis) • Hypocomplementemic ... gastrointestinal, and/or central