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diagnosis rheumatology differential neurology barre druginduced glomerulonephritis guillain guillainbarre lupus myelitis rapidly rpgn sle syndrome table transverse treatment vasculitis
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
Rapidly Progressive ... three primary pathophysiologic ... staining): • Low Complement ... RPGN #Rapidly #Progressive ... differential #diagnosis #algorithm
IGG-4 RELATED DISEASE WHAT? • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
dysfunction PATHOPHYSIOLOGY ... inflammation -> progressive ... - ↑ IgE, ↓ complement ... mimics excluded MANAGEMENT ... #Management #Rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
- ANA > 95% (IgG ... 90% - Low complement ... 80% - Low complement ... Usual therapeutic management ... druginduced #lupus #sle #comparison
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
presents with rapidly progressive ... Guillain-Barre Pathophysiology ... equina • GQ1b IgG ... Syndrome #diagnosis #management
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... index • Progression ... - Oligoclonal IgG ... levels • NMO-IgG ... Myelitis #diagnosis #management
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