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diagnosis rheumatology differential allergy hypersensitivity management pathophysiology reactions vasculitis acidosis champs clinicopathology comparison cryoglobulinemia cryoglobulins diabetes dmii erythematosus evaluation gammopathy
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... Chain deposition disease ... glomerulonephritis, type ... 1 (50%-80%), type ... #Low #Complement
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
antigen, leading to complement ... during hemolytic disease ... Complement activation ... #Classification ... Diagnosis #Reactions #Table
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Summary table of ... reaction, Haemolytic disease ... they activate complement ... #allergy #table ... #classification
Type 2 Diabetes - Screening, Diagnosis and Management Algorithm Lifestyle Modifications (Diet and Exercise) -> Start
Type 2 Diabetes ... and Management Algorithm ... relative with DM2 ... PCOS), Pancreatic Disease ... #DM2 #DMII #Classification
Lactic Acidosis - Overview and Pathophysiology Lactic acid is an endogenous substrate for gluconeogenesis, that is constantly
of underlying disease ... PLUS a pH < 7.35 TYPE ... Impaired O2 Delivery (DO2 ... Clearance • Other TYPE ... pathophysiology #classification
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... Types: • Type ... • Type III Often ... • Low serum C4 complement ... #classification
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... (Granulomatous disease ... against MPO • Complement ... #rheumatology #classification
IGG-4 RELATED DISEASE WHAT? • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
IGG-4 RELATED DISEASE ... fibroinflammatory disease ... • Pancreas: Type ... - ↑ IgE, ↓ complement ... • Classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Decade Skin Disease ... Classification: ... • Type-I Interferonopathies ... RNP antibodies, Complement
Preoperative Risk Evaluation Major Pre-Op Questions: 1. Does the patient have any modifiable risk factors that could be
Ischemic heart disease ... Insulin dependent DM ... event, follow ACC algorithm ... Risk Stratify Type ... What is the type
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