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diagnosis classification differential rheumatology hypersensitivity nephrology vasculitis allergy comparison glomerular nephrotic reactions workup acuteglomerulonephritis bergersdisease champs clinical clinicopathology compared cryoglobulinemia
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... Chain deposition disease ... , type 1 (50%-80% ... ), type II (80-90% ... #Low #Complement
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Idiopathic • Normal Complement ... involvement: Anti-GBM Disease ... differential #diagnosis #algorithm
Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
Summary table of ... Allergen-specific lgE causes ... reaction, Haemolytic disease ... Post-streptococcal glomerulonephritis ... #allergy #table
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
antigen, leading to complement ... during hemolytic disease ... Complement activation ... Post-streptococcal glomerulonephritis ... Diagnosis #Reactions #Table
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... , Glomerulonephritis ... against MPO • Complement
Comprehensive pathogenesis of IgA Nephropathy (i.e Berger’s Disease). IgA Nephropathy is the most common cause of
the most common cause ... of Glomerulonephritis ... - What type of Hypersensitivity ... Relationship of complement ... AcuteGlomerulonephritis #Glomerulonephritis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Skin ulcers - Glomerulonephritis ... Cryoglobulins Cause ... • Autoimmune diseases ... • Low serum C4 complement
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
for glomerular disease ... or alternative complement ... infections are common causes ... cryoglobulinemias (types ... workup #diagnosis #glomerulonephritis
Recommended initial testing for patients being evaluated for glomerular disease 1) 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... or alternative complement ... infections are common causes ... cryoglobulinemias (types ... diagnosis #initial #testing
Preoperative Risk Evaluation Major Pre-Op Questions: 1. Does the patient have any modifiable risk factors that could be
event, follow ACC algorithm ... Risk Stratify Type ... What is the type ... surgery Stress Testing ... preoperative stress testing
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