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diagnosis differential management rheumatology stratification antibiotics aspergillus betadglucan biomarkers bloodproduct causes classification comparison contents erythematosus evaluation febrile fungal galactomannan immunecompromised
“Step by Step” – the new kid on the block – aims to risk stratify this
for each of the components ... of the algorithm ... an infant with fever ... Infant #StepByStep #Algorithm ... Stratification #Fever
Blood Product Components, Contents, Volume and Shelf Life Whole blood (autologous or directed donations) - RBC and
Blood Product Components ... coagulation factors, complement ... #BloodProduct #Components ... Contents #Volume #Hematology ... #Management #Table
Causes of Fever in the Immunocompromised Host - Differential Diagnosis Algorithm Structural Defect - Asplenia/HypospIenism • Bacteremia/Septic
Causes of Fever ... Encapsulated Bacteria Cell ... Periodontal Disease Complement ... Infection #Fever ... #Causes #Hematology
Preoperative Risk Evaluation Major Pre-Op Questions: 1. Does the patient have any modifiable risk factors that could be
Key Components: ... or family - Ever ... physical exam - Key components ... event, follow ACC algorithm ... Stable patients
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Urticaria and hypocomplementemia ... Coronary arteries - Fever ... episcleritis as well ... Vasculitis: • Fevers ... against MPO • Complement
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... anti-Smith Ab, low complements ... to: Arthritis, Fever ... Thrombosis highest risk ... : • Chronic B-cell
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
Polysaccharide cell ... wall component ... infection (IFI) in hematologic ... of Aspergillus cell ... useful in high risk
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