Hypocomplementemia complement sle algorithm systemic table classification types management sjogrens

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Cryoglobulinemia Summary

Cryoglobulins:
• Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below

activate the immune system ... diseases: - 10% SLE ... • Low serum C4 complement ... erythematosus (SLE ... #classification

Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease

Sjogren's Syndrome ... overlaps with RA, SLE ... Cytopenia: 2% • Hypocomplementemia ... IV RTA, TYPE I ... Rheumatology #Diagnosis #Management

SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and

SLE (Systemic Lupus ... anti-Smith Ab, low complements ... Skin Disease Classification ... dermatomyositis, Sjogren ... Kikuchi disease • Type-I

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