16 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
RPGN has three primary ... pathophysiologic causes ... staining): • Low ... Complement: Post-strep ... differential #diagnosis #algorithm
Etiologies of Hypoaldosteronism

Hyporeninemic Hypoaldosteronism (Low Renin, Low Aldosterone)
 - Diabetic Nephropathy 
 - NSAIDs
Non-Hyporeninemic Hypoaldosteronism (Normal
Hypoaldosteronism (Low ... Chronic heparin - Primary ... insufficiency - Critical ... Aldosterone #Comparison #Table ... #Causes
Hypokalemia - Differential Diagnosis
Poor Intake 
 - Starvation
 - Anorexia
GI Losses 
 - Vomiting / NG
Ureterosigmoidostomy Urinary ... Differential #Diagnosis #Low ... #Potassium #Table ... #Classification ... #Causes
Hypomagnesemia - Etiologies by Mechanism

Decreased GI Uptake 
 - Poor dietary intake (particularly common in alcoholics)
inhibitors - Primary ... Differential #Diagnosis #Low ... #Magnesium #Table ... #Classification ... #Causes #Workup
Adrenal Insufficiency Differential Diagnosis Algorithm
Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Differential Diagnosis Algorithm ... Clinical suspicion ... Weakness, fatigue, nausea ... baseline ACTH - Primary ... insufficiency • Low
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... in >90% - Low ... complement - Rare ... complement - 50 ... sle #comparison #table
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... Urticaria and hypocomplementemia ... against MPO • Complement ... (Low levels mixed ... #rheumatology #classification
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
time you have a case ... normal volume-based algorithm ... can be high or low ... water intake (Primary ... differential #diagnosis #table
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Syndrome: • Clinical ... factor level • Low ... serum C4 complement ... diagnosis #types #classification
Perhaps quite too often, the knee-jerk reaction to an elevated Troponin is to call our friends
are typically able ... us to treat the primary ... cause. ... #diagnosis #algorithm ... echocardiogram #management #clinical