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diagnosis rheumatology differential management medium size syndrome anca cryoglobulinemia cryoglobulins cutaneous ddxof dermatology disease erythematosus im lupus rheum signs sjogrens
A System for Vasculitides #Diagnosis #IM #Rheum #Vasculitis #Small #Medium #Large #Vessel #Size #Classification #ANCA #Differential
A System for Vasculitides ... #Small #Medium ... #Large #Vessel # ... Size #Classification ... #Differential #Algorithm
Vasculitis - Break down based on vessel size Distribution of vessel involvement by large vessel vasculitis,
Large vessel vasculitis ... affects large arteries ... affects medium arteries ... Small vessel vasculitis ... #Classification
Classification of Vasculitis Vasculitis of large vessels - Arteritis temporalis (giant-cell arteritis) - Takayasu
Classification of ... of large vessels ... of small vessels ... syndrome - Behcet ... dermatomyositis #Size #Classification
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
abnormalities SMALL ... LARGE VESSEL ... : • Behçet Syndrome ... against MPO • Complement ... #rheumatology #classification
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
Findings: • Small ... ulceration Small ... Polyarteritis nodosa Large ... : • Temporal arteritis ... : • Behcet Disease
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
multiple organs, small-vessel ... vasculitis and ... large-vessel vasculopathy ... Arterial (MCC-small ... Medium and large
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
discrepancies LARGE ... and infarcts SMALL ... ) • Hypocomplementemic ... • Behcet syndrome ... chorioretinitis, CNS large
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
arthralgia, and arthritis ... • Low serum C4 complement ... • Cutaneous small-vessel ... SLE), rheumatoid arthritis ... diagnosis #types #classification
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Skin Disease Classification ... inflammation of the small ... and large bowel ... RNP antibodies, Complement
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Cytopenia: 2% • Hypocomplementemia ... nervous system: small-fiber ... ) • Cutaneous vasculitis ... Arthralgia and Arthritis ... cell lymphoma • Large
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