13 results
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... and branches • GCA ... against MPO • Complement ... #rheumatology #classification
Vasculitis Management - ACR/VF 2021 Guidelines for Treatment & Management
 • Giant Cell Arteritis (GCA)
 •
Vasculitis Management ... • Giant Cell Arteritis ... arteritis (TAK) ... Sources: GCA ... ACR2021 #Guidelines #algorithm
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
staining): • Low Complement ... Idiopathic • Normal Complement ... ANCA (C-ANCA): GPA ... #Vasculitis #differential ... #diagnosis #algorithm
2021 ACR/VF Guidelines for Management of Giant Cell Arteritis (GCA)

#GiantCell #Arteritis #GCA #ACR2021 #Management #rheumatology #algorithm
of Giant Cell Arteritis ... (GCA) #GiantCell ... #Arteritis #GCA ... #rheumatology #algorithm ... #vasculitis
Giant Cell Arteritis (GCA) - Vasculitis Management Algorithm - ACR/VF 2021 Guidelines
 • Visual Symptoms/Loss or
Giant Cell Arteritis ... (GCA) - Vasculitis ... Management Algorithm ... #GCA #Vasculitis ... ACR2021 #Guidelines #algorithm
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Elevated ESR and CRP GCA ... develop in pts with GCA ... (Glomerulonephritis ... Elevated AST ALT • Hypocomplementemia ... ) • Hypocomplementemic
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Skin ulcers - Glomerulonephritis ... arthralgia, and arthritis ... • Low serum C4 complement ... SLE), rheumatoid arthritis ... diagnosis #types #classification
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Polyangiitis (GPA ... • Pauci-immune vasculitis ... • Giant cell arteritis ... pneumonia with glomerulonephritis ... Granulomatous vasculitis
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
antigen, leading to complement ... Complement activation ... Post-streptococcal glomerulonephritis ... , rheumatoid arthritis ... Hypersensitivity #Types #Classification
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
antigens, leading to complement ... they activate complement ... Examples: Rheumatoid arthritis ... Post-streptococcal glomerulonephritis ... allergy #table #classification