Hypocomplementemia complement vasculitis algorithm workup testing hemolytic initial cold disease

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Hemolytic Anemia - Differential Diagnosis Algorithm
• Sickle cells - Consider sickle cell disease (diverse genotypes):

Differential Diagnosis Algorithm ... Agglutination - Cold ... cardiac valve, vasculitis ... #workup #hematology ... #testing

Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
1. Cold Agglutinins (CAD)
2. Donath-Landsteiner

Cryoglobulins (Vasculitic ... Positive Coombs testing ... post infectious setting ... temperatures by fixing complement ... #hemolytic #anemia

Recommended initial testing for patients being evaluated for glomerular disease

24-hour urine collection - Quantify proteinuria.

Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.

LDH - Assess for hemolysis ... or alternative complement ... for ANCA-related vasculitis ... #workup #diagnosis ... #initial #testing

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