15 results
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... Testing Algorithm ... evaluation or workup ... • Screen for secondary ... (common causes
Hypereosinophilia Different Diagnosis and Workup
Secondary causes are broad so start with a med review, the most
Diagnosis and Workup ... Secondary causes ... the most common cause ... the US inpatient setting ... #algorithm
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins Cause ... hematological disorders ... Type III Often Secondary ... • Low serum C4 complement
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... or alternative complement ... infections are common causes ... for ANCA-related vasculitis ... #workup #diagnosis
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... AIHA Primary Secondary ... Secondary Cold ... Positive Coombs testing ... temperatures by fixing complement
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Differential Diagnosis Algorithm ... in primary or secondary ... - Collagen disorders ... deficiency Work
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
Causes of Secondary ... Hypertension - Workup ... Coarctation of aorta, Vasculitis ... Neurologic disorders ... #Hypertension #Workup
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Differential Diagnosis Algorithm ... cardiac valve, vasculitis ... Consider RBC membrane disorder ... #workup #hematology ... #testing
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... or alternative complement ... infections are common causes ... for ANCA-related vasculitis ... glomerular #disease #workup
Causes of Primary Amenorrhea - Differential Diagnosis Algorithm
No onset of menarche by age 16 with secondary
Differential Diagnosis Algorithm ... by age 16 with secondary ... age 14 without secondary ... Functional (e.g. eating ... disorder, weight