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diagnosis differential nephrology aki acute renal rheumatology kidney workup disease glomerulonephritis hematuria kidneyinjury nephrotic testing acutekidneyinjury blood cardiology cryoglobulinemia cryoglobulins
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... - Skin, glomeruli ... : - Kidneys: glomerular ... against MPO • Complement ... #rheumatology #classification
Acute Kidney Injury - Classification Prerenal: • Dehydration • Heart failure (a.k.a. cardiorenal syndrome) • Liver failure
Acute Kidney Injury ... - Classification ... - Small vessel vasculitis ... - TTP/HUS • Glomerular ... tubular necrosis (causes
Causes of Acute Kidney Injury - Differential Diagnosis Framework Pre-Renal Post-Renal Intrinsic Renal: • Tubules (ATN) • Glomerular:
Causes of Acute ... Kidney Injury - ... Tubules (ATN) • Glomerular ... #KidneyInjury #Causes ... Differential #Diagnosis #Algorithm
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
Causes of Hematuria ... Differential Diagnosis Algorithm ... benign sediment (injury ... Differential #Diagnosis #Algorithm ... #Causes
Drug Induced Kidney Injury • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy • Osmotic
Induced Kidney Injury ... therapy • Osmotic injury ... Vitamin C • Glomerular ... : Drug induced vasculitis ... differential #diagnosis #algorithm
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
or dipstick) Glomerular ... Immune mediated injury ... of Glomerular Bleeding ... Diagnostic of GN or vasculitis ... Suggestive of glomerular
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... Idiopathic • Normal Complement ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm
Causes of Seizures - Differential Diagnosis Algorithm Unprovoked - Epilepsy: • Focal: Simple, Complex • Generalized: Absence,
Causes of Seizures ... Differential Diagnosis Algorithm ... malformation, Aneurysm, Vasculitis ... Traumatic brain injury ... #Causes #neurology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
causing endothelial injury ... • They can cause ... Cryoglobulins Cause ... • Low serum C4 complement ... diagnosis #types #classification
Acute Kidney Injury (AKI) - Differential Diagnosis Framework Pre-Renal: • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... Emboli, Thrombosis, Vasculitis ... Acute #Kidney #Injury ... Diagnosis #nephrology #causes ... #algorithm
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