3 results
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... false negative (small ... hypergammaglobulinemia, ↑ acute ... rheumatoid factor), ± hypocomplementemia ... No necrosis, No vasculitis
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
abnormalities SMALL ... Urticaria and hypocomplementemia ... pain, infarct • Small ... against MPO • Complement ... #rheumatology #classification
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Skin Disease Classification ... : • Acute cutaneous ... Pleural effusions • Acute ... inflammation of the small