9 results
IgA Vasculitis – Henoch Scholein Purpura: Pathogenesis and Clinical Findings

 - Infectious Agents - 50% have
IgA Vasculitis – ... Activation of complement ... histopathologic term for small ... - Cutaneous small ... periumbilical region), nausea
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
abnormalities SMALL ... Schonlein Purpura (IgA ... tract, and often causes ... against MPO • Complement ... #rheumatology #classification
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low Complement ... : IgA nephropathy ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... • Low serum C4 complement ... • IgA vasculitis ... • Cutaneous small-vessel ... diagnosis #types #classification
Acute Kidney Injury - Classification
Prerenal:
 • Dehydration
 • Heart failure (a.k.a. cardiorenal syndrome)
 • Liver failure
- Classification ... emergency - Small ... vessel vasculitis ... tubular necrosis (causes ... Kidney #Injury #Classification
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
and infarcts SMALL ... tract, and often causes ... , IgA (cmpkx deposits ... Elevated AST ALT • Hypocomplementemia ... ) • Hypocomplementemic
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Allergen-specific lgE causes ... antigens, leading to complement ... days - Examples: Acute ... they activate complement ... allergy #table #classification
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
disorders, or other causes ... • Secondary Causes ... - APLS • Acute ... • Ig A vasculitis ... ANCA associated small
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Skin Disease Classification ... : • Acute cutaneous ... Pleural effusions • Acute ... inflammation of the small