7 results
A System for Vasculitides 

#Diagnosis #IM #Rheum #Vasculitis #Small #Medium #Large #Vessel #Size #Classification #ANCA #Differential
#Small #Medium ... #Large #Vessel # ... Size #Classification ... #ANCA #Differential ... #Algorithm #Ddxof
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
abnormalities SMALL ... tract, and often causes ... , arthritis LARGE ... against MPO • Complement ... #rheumatology #classification
Vasculitis - Break down based on vessel size 
Distribution of vessel involvement by large vessel vasculitis,
Large vessel vasculitis ... Small vessel vasculitis ... can affect any type ... basement membrane; ANCA ... #Classification
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... • Low serum C4 complement ... DDX: • ANCA (Antineutrophil ... • Cutaneous small-vessel ... #classification
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
discrepancies LARGE ... and infarcts SMALL ... tract, and often causes ... ) • Hypocomplementemic ... chorioretinitis, CNS large
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
anti-Smith Ab, low complements ... Skin Disease Classification ... Kikuchi disease • Type-I ... inflammation of the small ... and large bowel
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Cytopenia: 2% • Hypocomplementemia ... • Can cause TYPE ... nervous system: small-fiber ... ) • Cutaneous vasculitis ... cell lymphoma • Large