13 results
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... glomerulonephritis, type ... 1 (50%-80%), type ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cryoglobulins: - Composed ... factor level • Low ... serum C4 complement ... #classification
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... Urticaria and hypocomplementemia ... against MPO • Complement ... (Low levels mixed ... #rheumatology #classification
Hypokalemia - Differential Diagnosis
Poor Intake 
 - Starvation
 - Anorexia
GI Losses 
 - Vomiting / NG
and 2, but not type ... 4) - Salt wasting ... Differential #Diagnosis #Low ... Potassium #Table #Classification ... #Causes
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
in monitoring low-level ... or alternative complement ... infections are common causes ... for ANCA-related vasculitis ... cryoglobulinemias (types
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Agglutinin Disease 3 Types ... Cryoglobulins (Vasculitic ... originate from a low-grade ... Positive Coombs testing ... temperatures by fixing complement
Recommended initial testing for patients being evaluated for glomerular disease
1) 24-hour urine collection - Quantify proteinuria.
in monitoring low-level ... or alternative complement ... infections are common causes ... for ANCA-related vasculitis ... cryoglobulinemias (types
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
immunosuppression in the setting ... transplants, as compared ... by transplant type ... Diagnosis and classification ... to 50% of PTLD cases
Erythemas Summarized
Erythema ab igne
 • A dermatosis that results from repeated exposure to heat (fires, heating
to heat (fires, heating ... form of delayed-type ... of necrotizing vasculitis ... Usually composed ... #dermatology #compared
USMLE Epidemiology and Biostatistics Summary
Meta-Analysis: pools data from several studies (greater power), limited by quality/bias of
Proves cause-effect ... prevalence is low ... then PPV will be low ... measurements Type ... when it’s true Type