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diagnosis rheumatology differential champs classification coccidioidomycosis comparison druginduced fever hematology infectiousdiseases low lupus mnemonic related sjogrens sle syndrome table treatment
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... Chain deposition disease ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... pseudotumor 4 phenotypes ... rheumatoid factor), ± hypocomplementemia ... #Related #Disease ... #diagnosis #management
IGG-4 RELATED DISEASE WHAT? • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
IGG-4 RELATED DISEASE ... fibroinflammatory disease ... - ↑ IgE, ↓ complement ... mimics excluded MANAGEMENT ... #Management #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... (Granulomatous disease ... atherosclerotic disease ... against MPO • Complement
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
- ANA > 95% (IgG ... 90% - Low complement ... 80% - Low complement ... Usual therapeutic management ... Evolution: Chronic disease
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
multisystemic disease ... associated with other diseases ... Cytopenia: 2% • Hypocomplementemia ... demyelinating disease ... Rheumatology #Diagnosis #Management
Coccidioidomycosis (Valley Fever) - Diagnosis and Management Summary WHAT? • Coccidioidomycosis due to Coccidioides immitis or Coccidioides
Diagnosis and Management ... for disseminated disease ... analysis using complement ... check for IgM and IgG ... Fever #Diagnosis #Management
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