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differential nephrology adrenal amenorrhea cardiology criticalcare endocrinology glomerular glomerulonephritis gynecology hematology hypokalemia insufficiency management nephrotic obgyn rheumatology vasculitis workup acth
Causes of Hypocomplementemia - CHAMPS Mnemonic C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis H - Heavy Chain deposition
Causes of Hypocomplementemia ... @AnnKumfer #Hypocomplementemia ... #Low #Complement ... CHAMPS #Mnemonic #diagnosis
Complement Deficiency Testing Algorithm • Normal CH50 and AH50 AND High suspicion for complement deficiency •
Complement Deficiency ... Testing Algorithm ... #Deficiency #Testing ... #Algorithm #hematology ... #diagnosis
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... staining): • Low ... Complement: Post-strep ... #differential #diagnosis ... #algorithm #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... against MPO • Complement ... (Low levels mixed
Adrenal Insufficiency Differential Diagnosis Algorithm Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Algorithm Clinical ... Weakness, fatigue, nausea ... , hypoglycemia Testing ... Baseline plasma ACTH Low ... insufficiency • Low
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH Early am cortisol < 3
Algorithm - Evaluation ... unclear (often the case ... then go to stim testing ... primary AI - Low ... #Algorithm #ACTH
Hypokalemia Evaluation Algorithm Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
Hypokalemia Evaluation Algorithm ... from other causes ... suggests extra-renal causes ... consumption • Low ... #Hypokalemia #diagnosis
Causes of Secondary Amenorrhea - Differential Diagnosis Algorithm Absence of menses for more than 3 cycles or
Causes of Secondary ... - Differential Diagnosis ... Algorithm Absence ... FSH, Low estrogen ... #Algorithm #Causes
Causes of Primary Amenorrhea - Differential Diagnosis Algorithm No onset of menarche by age 16 with secondary
- Differential Diagnosis ... Algorithm No onset ... Etiology - High FSH, Low ... Functional (e.g. eating ... #Algorithm #Causes
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
Recommended initial testing ... in monitoring low-level ... or alternative complement ... infections are common causes ... #workup #diagnosis
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