8 results
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... Chain deposition disease ... 1 (50%-80%), type ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
, seasonal hay fever ... antigen, leading to complement ... during hemolytic disease ... Complement activation ... #Classification
Summary table of types of hypersensitivity reactions. 
Type 1
 - Mediators: lgE
 - Antigen Form: Soluble
Anaphylaxis, Hay fever ... antigens, leading to complement ... reaction, Haemolytic disease ... they activate complement ... allergy #table #classification
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often involved • Hypocomplementemic ... Urticaria and hypocomplementemia ... Vasculitis: • Fevers ... against MPO • Complement ... #rheumatology #classification
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Disease 3 Types ... Agglutinin Disease ... temperatures by fixing complement ... Symptoms: High fevers ... #agglutinin #disease
Factors that May Affect Fetal Oxygenation - Differential Diagnosis Algorithm

Excessive Uterine Activity:
 • Hyperstimulation
 • Placental
Differential Diagnosis Algorithm ... • Respiratory disease ... Conditions: • Fever ... Vasculopathy (SLE, Type ... Differential #Diagnosis #Algorithm
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... anti-Smith Ab, low complements ... Classification: ... • Type-I Interferonopathies ... to: Arthritis, Fever
Preoperative Risk Evaluation

Major Pre-Op Questions:
1. Does the patient have any modifiable risk factors that could be
or family - Ever ... Ischemic heart disease ... event, follow ACC algorithm ... Risk Stratify Type ... What is the type