5 results
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... Atypical HUS, autoimmune ... @AnnKumfer #Hypocomplementemia ... #Low #Complement
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... node), high serum IgG4 ... rheumatoid factor), ± hypocomplementemia ... with increased IgG4 ... Disease #diagnosis #management
IGG-4 RELATED DISEASE

WHAT?
 • A chronic, immune-mediated fibroinflammatory disease with tumefactive infiltration of IgG4+ plasma cells
Pancreas: Type 1 AIP (Autoimmune ... malignant, or other autoimmune ... - ↑ IgE, ↓ complement ... mimics excluded MANAGEMENT ... #Management #Rheumatology
Algorithm for the Management of initial presentation as well as relapse of AIP and IDCP. AIP,
Algorithm for the ... Management of initial ... AIP, autoimmune ... pancreatitis; IgG4 ... #AIP #Algorithm
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
be any age) Autoimmune ... Cytopenia: 2% • Hypocomplementemia ... 16% Liver: • Autoimmune ... extraglandular autoimmune ... Rheumatology #Diagnosis #Management