5 results
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... with response to treatment ... rheumatoid factor), ± hypocomplementemia ... + cells" Treatment ... phenotypes #workup #treatment
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
- ANA > 95% (IgG ... 90% - Low complement ... constitutional symptoms • Treatment ... 80% - Low complement ... life-threatening • Treatment
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Liver Injury (DILI ... Stepwise Diagnosis Algorithm ... non-essential drug/HDS treatments ... Autoantibody titres, ↑ IgG ... Injury #Diagnosis #Algorithm
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Induced Lupus (DIL ... - ANA > 95% (IgG ... 90% - Low complement ... constitutional symptoms • Treatment ... rheumatology #diagnosis #treatment
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Cytopenia: 2% • Hypocomplementemia ... • Nephrogenic DI ... Adenocarcinoma Treatment