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diagnosis oncology allergy aplastic causes erythematosus lupus macrophage mas mds myelodysplasia myelodysplastic secondary sle syndromes systemic thrombocytosis tryptase
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
malignancies • Anemia ... inflammatory disorders ... Myelodysplastic syndrome ... myeloid leukemia ... Diagnosis #Causes #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... • (Peripheral eosinophilia ... - infiltrates (anemia ... • Tumor lysis syndrome ... #Hematology #Oncology
Approach to Elevated Tryptase - Differential Diagnosis Framework The DDx of elevated tryptase can be broken down
ESRD & CAD • Eosinophilic ... GI Disorders ... • Mast cell activation ... syndrome • Mastocytosis ... #Diagnosis #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
ecchymoses, mucosal bleeding ... - Hepatitis, eosinophilic ... virus (EBV) • Leukemia ... #oncology #hematology ... #diagnosis #management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
purpura to mucosal bleeding ... with leukopenia, anemia ... 10,000 ng/mL • Hyponatremia ... #Management #Hematology ... #Rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... Marrow Failure • Chronic ... Myelogenous Leukemia ... blood count with differential ... #diagnosis #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... with Lupus: • Chronic ... B-cell activation ... Hodgkin lymphoma and leukemia ... Erythematosus #Diagnosis #Rheumatology
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