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diagnosis algorithm aflp causes comparison injury acute coagulation common cvid deficiencies deficiency fatty gap globulin hellp hypogammaglobulinemia icp immunodeficiency immunology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
• Infectious: Hepatitis ... hepatitis, Acute ... , Alcoholic Hepatitis ... Sepsis, Viral Hepatitis ... Acute #algorithm #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Wilson's • Pregnancy ... • Drugs • AIH ... • Alcoholic hepatitis ... Others #LFTs #Hepatology
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
) • Advanced Liver ... , Viral hepatitis ... , Autoimmune • ... Septic shock, Obstetric ... comparison #diagnosis #hematology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
Autoimmune Hepatitis ... from subclinical disease ... Other Etiology of Hepatitis ... #Hepatitis #AIH ... #Hepatology
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Liver Disease in ... #Disease #Pregnancy ... #hepatology #obstetrics ... #hepatitis #comparison ... #differential #
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
of Pregnancy (AFLP ... infiltration) Differential ... Diagnosis: Viral Hepatitis ... #Pregnancy #hepatology ... #obstetrics #obgyn
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Autoimmune hepatitis ... melanoma, myeloma • Pregnancy ... Chronic viral hepatitis ... #injury #hepatitis ... diagnosis #algorithm #hepatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Liver diseases ... and hepatitis ... : Pneumonia • Autoimmune ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
HBV, EBV, VZV, hepatitis ... hepatitis, PBC, ... PSC, Viral hepatitis ... gastric tumors • Hematology ... #diagnosis #hematology
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