7 results
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Elevated Liver Function ... • NAFLD • Cirrhosis ... (>1000): • DILI ... injury) • Ischemic ... #Diagnosis #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Injury (DILI) ... Viral Hepatitis ... #Failure #Cirrhosis ... #Hepatology #gastroenterology ... #management #diagnosis
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
develops (DIC, ascites ... infiltration) Differential ... Hepatitis, Preeclampsia ... Pregnancy #hepatology ... #management #pathophysiology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Tests of synthetic function ... : < 1 • Cirrhosis ... #injury #hepatitis ... #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Failure (ALF): ... • Liver injury ... : < 1 • Cirrhosis ... #differential # ... Hepatology #transaminitis
Portal Hypertension - Differential Diagnosis
Portal Pressure = the pressure difference between the pressure in the portal
Diagnosis Portal ... hepatic synthetic function ... including R heart failure ... /acute hepatitis ... #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
65 years PBC Pathophysiology ... /Liver failure ... bile ducts Differential ... Viral hepatitis, ... #workup #hepatology