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rheumatology vasculitis dermatology classification cryofibrinogenemia cryoglobulins leukemia lymphadenopathy management mds miami mnemonic myelodysplasia myelodysplastic nonpalpable palpable purpura sjogrens syndromes types
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
- Differential ... Primary: 50% ... Leukocytoclastic Vasculitis Secondary ... Urticarial/LCV) - Cryoglobulinemic ... Disease • Cogan syndrome
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... purple, hemorrhagic skin ... /Quantity: • Primary ... vasculitis/HSP • Cryoglobulinemia ... #Diagnosis #hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... - Purpura - Skin ... Cryoglobulins Cause ... Type III Often Secondary ... Henoch-Schönlein purpura) • Cutaneous
MIAMI Mnemonic for Differential Diagnosis of Lymphadenopathy Malignancies - Kaposi sarcoma, leukemias, lymphomas, metastases, skin neoplasms Infections -
lymphomas, metastases, skin ... Bartonella), chancroid, cutaneous ... lymphogranuloma venereum, primary ... and secondary syphilis ... arthritis, Sjögren syndrome
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 Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Primary (essential ... Associated Disorders ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
other diseases • Secondary ... Hypocomplementemia • Can cause ... ) • Cutaneous vasculitis ... Nephrogenic DI Hematologic ... Vasculitis: • 7%, Cryoglobulinemia
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
with GCA or as primary ... Rash, arthritis Primary ... tract, and often causes ... / ANCA + MPO) Cryoglobulinemic ... #Diagnosis #Rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... DDX: Rule Out Secondary ... blood count with differential ... #diagnosis #hematology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
+ distinctive primary ... bone marrow and secondary ... CLL -> Invade Skin ... #Leukemia #Hematology ... #Oncology #Diagnosis
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