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rheumatology vasculitis dermatology classification agglutinin algorithm anemia cold cryofibrinogenemia disease hemolytic leukemia lymphadenopathy management mds miami mnemonic myelodysplasia myelodysplastic nonpalpable
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... - Purpura - Skin ... Cause Organ Damage ... Type III Often Secondary ... Henoch-Schönlein purpura) • Cutaneous
Vasculitis Involving the Skin - Differential Diagnosis Framework Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis Secondary: CTD: SLE, RA
- Differential ... Primary: 50% ... Leukocytoclastic Vasculitis Secondary ... Urticarial/LCV) - Cryoglobulinemic ... Disease • Cogan syndrome
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... purple, hemorrhagic skin ... /Quantity: • Primary ... vasculitis/HSP • Cryoglobulinemia ... #Diagnosis #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Primary (essential ... Associated Disorders ... • Negative causes ... Antiphospholipid syndrome ... hematology
MIAMI Mnemonic for Differential Diagnosis of Lymphadenopathy Malignancies - Kaposi sarcoma, leukemias, lymphomas, metastases, skin neoplasms Infections -
lymphomas, metastases, skin ... Bartonella), chancroid, cutaneous ... lymphogranuloma venereum, primary ... and secondary syphilis ... arthritis, Sjögren syndrome
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 Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Abnormalities in primary ... or secondary hemostasis ... Vasculitis - Collagen disorders ... • Skin biopsy ... #Causes #dermatology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... 15% of AIHA Primary ... Agglutinin Syndrome ... presentation) • Cutaneous ... younger pts) Differential
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... aphthous ulcers, cutaneous ... strong sign of cutaneous ... Serologies for Cryoglobulins ... #diagnosis #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
other diseases • Secondary ... Hypocomplementemia • Can cause ... ) • Cutaneous vasculitis ... Nephrogenic DI Hematologic ... Vasculitis: • 7%, Cryoglobulinemia
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
with GCA or as primary ... Rash, arthritis Primary ... tract, and often causes ... / ANCA + MPO) Cryoglobulinemic ... #Diagnosis #Rheumatology
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