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Adrenal Insufficiency Differential Diagnosis Algorithm Clinical suspicion: Weakness, fatigue, nausea, musculoskeletal pain, dizziness, volume depletion, abdominal pain,
Differential Diagnosis Algorithm ... Low Cortisol Response ... insufficiency • Low ... Differential #Diagnosis #Algorithm ... #endocrinology
Hypercortisolism (Cushing syndrome) - Simplified Differential Diagnosis Algorithm Exogenous (ACTH-independent) Endogenous • ACTH-dependent: - ACTH-secreting
Differential Diagnosis Algorithm ... Exogenous (ACTH-independent ... : - ACTH-secreting ... Differential #Diagnosis #Algorithm ... #endocrinology
Diagnosis Adrenal Insufficiency - Algorithm Step 1) Screening Test: 6-8AM Cortisol Level - Early morning cortisol levels
Insufficiency - Algorithm ... specificity for AI (but low ... - Low ACTH is ... Insufficiency #Algorithm ... #Stimulation #Endocrinology
Adrenal Insufficiency Diagnosis Algorithm - Evaluation of HPA Axis Response to ACTH Early am cortisol < 3
Insufficiency Diagnosis Algorithm ... Axis Response to ACTH ... primary AI - Low ... Insufficiency #Diagnosis #Algorithm ... #Test #Endocrinology
Benign Adrenal Mass - Differential Diagnosis Algorithm Hyperplasia - Often Bilateral • Congenital Adrenal Hyperplasia • ACTH
Differential Diagnosis Algorithm ... Hyperplasia • ACTH ... Dependent • ACTH ... High DHEAS • Low ... #Endocrinology
Primary vs Secondary Adrenal Insufficiency - Pathophysiology Primary AI = adrenal glands themselves are the problem. This
aldosterone will be low ... , while ACTH AND ... Low ACTH leads to ... stimulation, thus low ... Pathophysiology #endocrinology
Adrenal Insufficiency - Differential Diagnosis Workup Algorithm Primary Adrenal Insufficiency: • Autoimmune primary adrenal insufficiency • Adrenoleukodystrophy,
Diagnosis Workup Algorithm ... apoplexy • Isolated ACTH-deficiency ... Diagnosis #Workup #Algorithm ... #endocrinology
Causes of Adrenal Insufficiency - Differential Diagnosis Algorithm ACTH-Dependent (Secondary): • Pituitary Dysfunction • Hypothalamic Dysfunction ACTH-Independent (Primary):
Differential Diagnosis Algorithm ... ACTH-Dependent ... Hypothalamic Dysfunction ACTH-Independent ... Differential #Diagnosis #Algorithm ... #Causes #endocrinology
Primary Adrenal Insufficiency: • ACTH stimulation test - Synthetic ACTH does not stimulate cortisol secretion because
between 8 and 9 AM - Low ... aldosterone - Low ... between 8 and 9 AM - Low ... - Low, because ... diagnosis #testing #endocrinology
Adrenal Insufficiency Diagnosis Algorithm Test 1: Baseline AM Cortisol - Beware of major normal value -
Insufficiency Diagnosis Algorithm ... pregnancy) Test 2: ACTH ... Insufficiency #Diagnosis #Algorithm ... #endocrinology
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