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diagnosis rheumatology vasculitis ana antinuclear classification cystic dcld disease glomerulonephritis lung management patterns progressive prs rapidly renal rpgn syndromes treatment
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... are associated ... • Nucleolar: Diffuse ... , Interstitial Pulmonary ... rheumatology #diagnosis #differential
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... Purpura Anti-GBM antibodies ... Glomerulonephritis • With associated ... pulmonary involvement ... #diagnosis #algorithm
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
EGPA) • Auto-antibodies ... Goodpasture's cause ... leading to diffuse ... hemorrhage (DAH) • Diffuse ... • IF staining patterns
Algorithm for Diagnosis of Diffuse Cystic Lung Disease (DCLD) Round, smooth cysts with normal lung parenchyma in
Algorithm for Diagnosis ... May have associated ... LCDD, SS Cyst pattern ... Disease #DCLD #pulmonary ... #differential
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... tract, and often causes ... - (C-ANCA) pattern ... : antibodies directed ... - (P-ANCA) pattern
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