12 results
Iron Deficiency in Heart Failure - Diagnosis and Treatment Algorithm
Diagnosis: Ferritin <100 ng/mL (absolute ID) OR
Iron Deficiency ... ng/mL (absolute ID ... 20% (functional ID ... HF with iron deficiency ... heartfailure #diagnosis #management
Iron Deficiency in Heart Failure
Pathophysiology:
Chronic heart failure leads to an increase in inflammatory cytokines → Inflammation
Iron Deficiency ... ng/mL (absolute ID ... 20% (functional ID ... ) Treatment - IV ... heartfailure #diagnosis #management
Causes of Iron Deficiency
 • Inadequate Intake: Vegetarian/vegan diet, Malnutrition
 • Increased Body Needs: Infants/preschoolers, Pregnancy,
Causes of Iron Deficiency ... Pregnancy, EPO treatment ... Inflammatory Disease (IBD ... , cancer) #Iron ... #Deficiency #differential
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
- Differential ... Inflammatory: • IBD ... effect following treatment ... malignancy • Iron ... deficiency anemia
Suspected Celiac Disease - Diagnosis Algorithm

Celiac disease suspected:
 • Signs and symptoms of celiac disease
 •
celiac disease • Iron-deficiency ... unresponsive to treatment ... without discernable cause ... microscopic colitis Differential ... Inflammatory (IBD
Fatigue and IBD Algorithm
 • 40-50% patients have fatigue despite clinical remission
 • Risk factors: BMI,
fatigue despite clinical ... Receptor (sTfR) to differentiate ... restricted diet/deficiency ... /other causes • ... Algorithm #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Cellular immune deficiency ... Drugs, Unknown cause ... Treatment: • ... of emergency, ICU ... Lymphohistiocytosis #diagnosis #management
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... intrinsic factor, IF) Clinical ... diarrhea related to IBD ... Check for IF ab Treatment ... #diagnosis #management
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Diagnosis and Management ... poor nutrition Clinical ... can lead to iron ... , or any other cause ... vasculitis Treatment
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... Differential Diagnosis ... Avoid ARBs • ICD ... support for patients clinically ... #cardiology #treatment