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hematology chronic leukemia lymphocytic aplastic arteritis classification cvid differential fungal gap gca giantcell globulin hemeonc hodgkins hypogammaglobulinemia immunodeficiency immunology lymphoma
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
: • Most common ... weeks without infection ... Hepatomegaly • Skin ... #workup #oncology ... #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
history of recurrent infections ... disease • Infectious ... community-acquired infections ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
immunophenotype Clinical ... Complications: 1) Infection ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc ... #diagnosis #management
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Headaches • Pale skin ... Neutropenia - recurrent infections ... Idiopathic • Infections ... #oncology #hematology ... #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... petechiae) • Frequent infections ... Most common cytopenia ... • Parvovirus infection ... #hematology #oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... (NSHL) - (most common ... Hodgkin Lymphoma Workup ... classification #hematology ... #oncology #management
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
with systemic, neurologic ... Diagnosis = clinical ... vasculitis vs infection ... required due to skip ... #Management
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... Include: • Viral infections ... gastric tumors • Hematology ... anemia • Other ... #hematology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
droppings • Most common ... Disseminated Infections ... pulmonary symptoms • Rheumatologic ... ) #Mycoses #InfectiousDiseases ... #Management #Infections
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