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diagnosis hematology differential management oncology algorithm aplastic arteritis chronic classification cll common cryofibrinogenemia cvid eosinophil eosinophilia gap gca giantcell globulin
Eosinophil Disorders Testing Algorithm INDICATIONS FOR TESTING: • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
Eosinophil Disorders ... drug reaction, infection ... Strongyloides infection ... symptoms (eg, skin ... Differential #diagnosis #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
purple, hemorrhagic skin ... - Hemolytic anemia ... SLE) - Viral infections ... APLS • Acute Infectious ... Differential #Diagnosis #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... procedures - Infection ... (CVID, WAS), (neurologic ... changes), high MCV anemia ... #Workup #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
hypogammaglobulinemia -> increased infection ... history of recurrent infections ... disease • Infectious ... community-acquired infections ... hypogammaglobulinemia #immunology #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
- Trauma - Infection ... Disseminated gonococcal infection ... deficiency Work ... cryoglobulins • Skin ... #dermatology #physicalexam
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... Headaches • Pale skin ... Neutropenia - recurrent infections ... Idiopathic • Infections ... #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... just beneath the skin ... petechiae) • Frequent infections ... • Parvovirus infection ... Syndromes #diagnosis #hematology
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Mycobacteria (NTM) Infections ... Factors For NTM Infections ... status NTM Cause ... • Disseminated infections ... : Chronic lung infections
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... weeks without infection ... Hepatomegaly • Skin ... • Neutropenia, anemia ... #oncology #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
cryoglobulinemia Associated Disorders ... Malignancy • Infections ... Diagnosis: • + Clinical ... cryoglobulins • Negative causes ... #hematology
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