9 results
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
• Affects 1:25,000 ... to 8 years Clinical ... Gastrointestinal inflammatory ... : Pneumonia • Autoimmune ... DDX - Other causes
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Relapsing-remitting course +++ Clinical ... features: 1. ... of infections) ... #diagnosis #management ... #rheumatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... such as infectious ... efficacious include IL-1 ... #Rheumatology # ... diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
cytokines, such as IL-1 ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
F • 3 peaks: 1) ... Aplastic Anemia Clinical ... and petechiae Causes ... Aplastic #Anemia #oncology ... #management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... salivary ducts Clinical ... Adenocarcinoma Treatment ... #Rheumatology # ... Diagnosis #Management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Syndrome - Overview ... within the first 1 ... decrease in HIV-1 ... cryptococcomas, cavitating pneumonia ... #Diagnosis #Management
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... Hodgkin Lymphoma - Clinical ... B symptoms in 1/ ... number of sites of disease ... #oncology #management
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
Inflammatory ... Anti-Matrilin-1 ... affected tissue Treatment ... Polychondritis #rheumatology ... #diagnosis #management