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hematology oncology algorithm anemia cancer chronic cll erythematosus hemophagocytic hlh inflammatory iris lupus lymphocytic mds myelodysplasia myelodysplastic reconstitution sle syndromes
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
mutations) • Immune ... Clinical Presentation ... virus (EBV) • Leukemia ... anemia Treatment ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... underlying genetic immune ... #diagnosis #management ... #treatment #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune ... Orange or Hep C Clinical ... weeks without infection ... cells can indicate disease ... Pure red cell aplasia
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Inflammatory Syndrome ... worsening of that disease ... cryptococcomas, cavitating pneumonia ... meningitis • Guidelines ... Diagnosis #Management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Causes • Anemia • Aplastic ... Significance (IDUS) • Immune ... Myeloproliferative Disease ... blood count with differential ... #diagnosis #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... fibromyalgia) • Infections ... context of primary immune ... Hodgkin lymphoma and leukemia
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
acute myeloid leukemia ... median age at diagnosis ... may result in an infection ... Network (NCCN) guidelines ... importance of clinical
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