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hematology hemophagocytic hlh activation algorithm anemia cancer differential immune iris mas oncology reconstitution summary
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Hemophagocytic Lymphohistiocytosis ... activation of macrophages ... production of pro-inflammatory ... #diagnosis #management ... #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
release of pro-inflammatory ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... with excessive macrophage ... #diagnosis #management ... #treatment #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Anemia Clinical ... Idiopathic • Infections ... virus (EBV) • Leukemia ... anemia Treatment ... #diagnosis #management
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
Syndrome - Overview ... worsening of that disease ... cryptococcomas, cavitating pneumonia ... meningitis • Guidelines ... #Diagnosis #Management
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
acute myeloid leukemia ... median age at diagnosis ... may result in an infection ... Network (NCCN) guidelines ... importance of clinical
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