IDSA guidelines rheumatology anemia hematology pediatrics clinical sle sicklecells diagnosis activation crisis scleroderma disease syndrome mas

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Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of

Syndrome (MAS) ... erythematosus [SLE ... #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology

$Scleroderma Renal Crisis (SRC) Clinical Presentation of Scleroderma Renal Crisis: 1) Acute kidney injury 2) Abrupt onset of hypertension 3)$

Clinical Presentation ... microangiopathic hemolytic anemia ... is unknown but may ... endothelial cell activation ... #rheumatology #nephrology

SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and

) Suspect: Clinical ... Clinical Features ... lymphopenia, low PLT • Anemia ... Chronic B-cell activation ... #Rheumatology

Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of

Rheumatology Workup ... the presence of anemia ... (to support a diagnosis ... ANA and RF (if clinical ... #testing #Rheumatology

Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear

extramedullary disease ... ALL: mediastinal mass ... -> AML: Blast crises ... - infiltrates (anemia ... #Leukemia #Hematology

Myelodysplastic syndromes current treatment algorithm 2018.

From Blood Cancer Journal, Published 24 May 2018

Myelodysplastic syndromes (MDS) are

median age at diagnosis ... tolerate anemia ... Network (NCCN) guidelines ... importance of clinical ... #algorithm #hematology

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