38 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... , ↓ Fibrinogen level ... of emergency, ICU ... #management #treatment
American College of Critical Care Medicine algorithm for time-sensitive, goal-directed stepwise management of hemodynamic support in
American College of Critical ... goal-directed stepwise management ... 2) Subsequent ICU ... goals—if shock ... #CriticalCare #
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... following: • Fever ... If no response HLH ... #management #treatment ... #hematology
Sepsis - Diagnosis and Management
Life-threatening organ dysfunction caused by a dysregulated host response to infection
SEPTIC SHOCK
Sepsis - Diagnosis ... infection SEPTIC SHOCK ... Clinical construct ... #SIRS #criticalcare ... #icu
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
syndromes Clinical ... is the main clinical ... ALT ↑ bilirubin level ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
regarding the diagnosis ... Hemochromatosis HH ... should be TS and SF level ... hemochromatosis #algorithm #diagnosis ... #management #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential Diagnosis ... Hepatic artery: Shock ... VZV • Trauma: Shock ... PBC, PSC, IgG4, HLH ... #algorithm #hepatology
Admitting in the ICU - Checklist
VITALS: If bad, stop and go see the patient immediately; you
esp in work-up/management ... of shock MICRO ... bedside echo is never ... Pearls #Checklist #diagnosis ... #workup #criticalcare
Pain, Agitation, and Delirium (PAD) in the ICU
Addressing the ICU Triad (PAD) can be accomplished through
tool to assess level ... will vary with clinical ... bradycardia. renal/liver ... #CriticalCare # ... diagnosis #management
Pancreatitis management checklist 
Evaluation to guide etiology & management 
 - RUQ ultrasound 
 - Calcium
ultrasound - Calcium level ... - Triglyceride level ... as for septic shock ... Pancreatitis #Checklist #Diagnosis ... #Management #CriticalCare