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hematology anesthesia workup blood differential hemophagocytic intraoperative lymphohistiocytosis product reactions treatment causes classification embolism embolus hodgkins hyperthermia hypotension lymphoma oncology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... • Clinical: fever ... , ↓ Fibrinogen level ... #management #treatment ... #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
following: • Fever ... lymph node, or liver ... If no response HLH ... #management #treatment ... #hematology
Intraoperative Circulatory Embolus - Guidelines for Crises in Anaesthesia Causes: thrombus, fat, amniotic fluid, air/gas. Signs: hypotension, tachycardia,
mainstay of initial management ... field to below level ... Embolism #VTE #Anesthesiology ... Intraoperative #Checklist ... #Diagnosis #Management
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia If prolonged or ≥ 39 C this is a
in Anaesthesia If ... Actively maintained fever ... Differential #Causes #Anesthesiology ... #Anesthesia #Checklist ... #Diagnosis #Management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... lymph node biopsy (diagnostic ... marrow biopsy - if ... Hodgkins #lymphoma #diagnosis ... #oncology #management
Hypotension - Guidelines for Crises in Anaesthesia Hypotension is commonly due to unnecessarily deep anaesthesia, the autonomic
Pause surgery if ... adult, 10 ml.kg-1 paediatric ... #Differential #Anesthesiology ... Intraoperative #Checklist ... #Diagnosis #Management
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
S/sx: Fever, flank ... thrombocytopenia, may be life-threatening ... donors (due to anti-HLA ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
S/sx: Fever, flank ... thrombocytopenia, may be life-threatening ... donors (due to anti-HLA ... #Transfusions #diagnosis ... #management #hematology
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