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hematology blood hemophagocytic lymphohistiocytosis product reactions treatment admissions admitting classification crisis endocarditis hodgkins icu influenza lymphoma myastheniagravis myasthenic oncology pancreatitis
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... • Clinical: fever ... , ↓ Fibrinogen level ... #management #treatment ... #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
following: • Fever ... lymph node, or liver ... If no response HLH ... #management #treatment ... #hematology
Pancreatitis management checklist Evaluation to guide etiology & management - RUQ ultrasound - Calcium
Pancreatitis management ... checklist Evaluation ... #Pancreatitis #Checklist ... #Diagnosis #Management ... #CriticalCare
Endocarditis checklist Initial evaluation • Peripheral blood cultures (three sets at three different sites) • Additional culture
Endocarditis checklist ... • Persistent fever ... #Endocarditis #checklist ... #criticalcare # ... diagnosis #management
Myasthenic Crisis Checklist - Myasthenia Gravis Evaluation - Chest X-ray and lung ultrasound (exclude other lung
Myasthenic Crisis Checklist ... workup or TSH level ... Pyridostigmine - New diagnosis ... MyastheniaGravis #Checklist ... #Management #CriticalCare
Admitting in the ICU - Checklist VITALS: If bad, stop and go see the patient immediately; you
Admitting in the ICU - Checklist ... esp in work-up/management ... bedside echo is never ... #diagnosis #workup ... #criticalcare
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Dyspnea • Fever ... lymph node biopsy (diagnostic ... marrow biopsy - if ... Hodgkins #lymphoma #diagnosis ... #oncology #management
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
S/sx: Fever, flank ... thrombocytopenia, may be life-threatening ... donors (due to anti-HLA ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
S/sx: Fever, flank ... thrombocytopenia, may be life-threatening ... donors (due to anti-HLA ... #Transfusions #diagnosis ... #management #hematology
Severe Influenza Checklist Diagnostic tests - Blood cultures x2 - Sputum gram stain & culture
Severe Influenza Checklist ... Diagnostic tests ... - Ferritin, liver ... diagnostic uncertainty ... #Management #CriticalCare
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