12 results
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
IFN-γ-activated ... affecting the lungs ... TB: • Fever • ... organ system: • Pleura ... TB #Diagnosis #Management
Tuberculosis Overview

10 million new M. tuberculosis infections/year
Facultative intracellular rod-shaped bacteria
Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
IFN-γ-activated ... affecting the lungs ... TB: • Fever • ... organ system: • Pleura ... TB #Diagnosis #Management
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
Pneumonia: • 3 syndromes ... It's usually low if ... of a "flu-like syndrome ... Focal pneumonia, pleural ... Infections #HIV #AIDS #pulmonary
Cryptogenic Organizing Pneumonia (COP)

Cryptogenic Organizing Pneumonia Overview:
 • Idiopathic form of organizing pneumonia
 • formerly BOOP
6th decades of life ... cough, dyspnea, fever ... Rare: pleural effusions ... , pleural thickening ... ILD #diagnosis #management
Atypical HUS - Hemolytic Uremic Syndrome
Unlike typical HUS, which is shigatoxin mediated, aHUS is not typically
Hemolytic Uremic Syndrome ... renal, cardiac, pulmonary ... obtain ADAMTS13 activity ... need the ADAMTS13 level ... complement blockade) Long
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... absence of intrinsic lung ... on radioactive lung ... supplemental oxygen if ... hepatopulmonary #syndrome
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... increased B-cell activity ... granulomas within the lungs ... Pulmonary: dyspnea ... acute sarcoidosis Pulmonary
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Clinical Features: Lungs ... : • Pleural effusions ... Serositis: • Pleural ... extremity edema, active ... and leukemia • Lung
Amiodarone Induced Lung Toxicity Summary

Who?
• 5% of patients
• Dose ≥ 400 mg per day

How?  Possible
Amiodarone half life ... and exudative pleural ... respiratory distress syndrome ... Fever 4. ... #diagnosis #management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Xerotrachea • NSIP: Pleural ... , INC risk PE, Pulmonary ... MALT Lymphoma • Lung ... muscarinic agonists • Active ... Rheumatology #Diagnosis #Management