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diagnosis rheumatology blood comparison cppd reactions activation classification deposition druginduced gout hodgkins laboratory lupus lymphoma macrophage mas oncology pseudogout pyrophosphate
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
juvenile idiopathic arthritis ... ALT ↑ bilirubin level ... Fibrin degradation products ... #Diagnosis #Management ... #Hematology #Rheumatology
Septic Arthritis - Diagnosis and Management Summary Clinical Exam: hot, swollen, pain with passive AND active ROM
Diagnosis and Management ... active ROM +/- fever ... necrosis, Lyme disease ... Workup: arthrocentesis ... 90% sensitive in pediatrics
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Studies in Rheumatic Diseases ... crystals (gout) or calcium ... profile (e.g., calcium ... #laboratory #workup
Pseudogout Summary - Calcium Pyrophosphate Deposition Disease (CPPD) Pathophysiology: Pyrophosphate produced by chondrocytes likely precipitates with calcium to
Pyrophosphate produced ... H's" especially if ... Crowned Dens Syndrome ... #Rheumatology # ... diagnosis #management
CPPD vs Gout == CPPD == Think About CPPD When: • Self-limited synovitis after surgery/trauma (> 65
• Underlying disease ... Pyrophosphate produced ... precipitates with calcium ... H's" Especially if ... • Metabolic syndrome
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Graft Versus Host Disease ... binds to serum calcium ... Borrellia (Lyme disease ... Transfusions #diagnosis #management ... #hematology #reactions
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... thiazidic, PPI, ACE, calcium-b ... • Immunologic Workup ... • Immunologic Workup ... Evolution: Chronic disease
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
binds to serum calcium ... Blood products contain ... of transfused products ... Transfusion #diagnosis #management ... #hematology #reactions
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
genes and gene products ... Hodgkin Lymphoma Workup ... number of sites of disease ... classification #hematology ... #oncology #management
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