11 results
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Pathogenesis and clinical ... Prader-Willi Syndrome Signs ... > Neonatal and infantile ... Syndrome #genetics #pathophysiology ... #peds #pediatrics
Floppy Baby Syndrome
 • Infantile Botulism
 • Acute Flaccid Myelitis
 • Guillain Barre
 • Neonatal Myasthenia
Baby Syndrome • Infantile ... Flaccid Myelitis • Guillain ... Myasthenia Gravis Clinical ... LMN signs - Assess ... tone, resistance, reflexes
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Pathophysiology ... meningococcal, H1N1) Clinical ... Clinical Features ... Decreased / Absent Reflexes ... management #treatment #neurology
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
Brudzinski’s Sign ... While the pathophysiology ... an involuntary reflex ... #Meningitis #Clinical ... #PhysicalExam #Pediatrics
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Pathogenesis and Clinical ... chromosome 21) Signs ... seizure, primitive reflexes ... AlzheimersDisease #Dementia #pathophysiology ... #geriatrics #diagnosis
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Pathogenesis and clinical ... bladder and rectal reflex ... Syndromes #diagnosis #pathophysiology ... #signs #symptoms ... #orthopedics #neurology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... transplantation CLINICAL ... depressed deep tendon reflexes ... the underlying pathophysiology ... diagnosis #management #neurology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
combination of the clinical ... lateral sclerosis Pathophysiology ... cellular function Clinical ... Increased Jaw Jerk reflex ... Lateral #Sclerosis #neurology
Woltman's sign of hypothyroidism- ...At the time of presentation, a physical examination was notable for the
Woltman's sign of ... the ankle jerk reflex ... video)...Woltman’s sign ... , is a neurologic ... #clinical #photo
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Transverse Myelitis - Clinical ... Spasticity - Reflexes ... • Bilateral signs ... diagnosis #management #neurology