13 results
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
HIV/HCV co-infection ... family history of HCC ... liver failure ... #Indications #management ... #hepatology
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Diagnosis and Management ... viremia or have cirrhosis ... , HIV, HCV. ... HAV immunity; Liver ... #Treatment #Hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... ACLF) Clinical Guidelines ... those with CLD (± cirrhosis ... #Chronic #Liver ... #Hepatology #gastroenterology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... , HBV, HCV, HEV, ... > 2 • NASH, Chronic ... hepatitis: < 1 • Cirrhosis ... diagnosis #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
hepatitis serologies, HCV ... hepatitis serologies, HCV ... > 2 • NASH, Chronic ... hepatitis: < 1 • Cirrhosis ... #differential #Hepatology
The 6 C’s of Primary Sclerosing Cholangitis (PSC)
PSC is a chronic, cholestatic, immune-mediated disease characterized by
PSC) PSC is a chronic ... disease management ... with UDCA remains common ... remain subject to clinical ... #summary #Hepatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
subclinical disease to acute ... liver failure ... - Symptoms of chronic ... arthralgias) are common ... #Hepatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Sarcoidosis) • Liver ... disease: Cirrhosis ... lung cancers, HCC ... inflammation (acute ... Comment on type
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Diagnosis and Management ... shunt (Type 2) Clinical ... • Dyspnea - Common ... with or without cirrhosis ... #treatment #hepatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... Autoimmunity • Chronic ... disease • Liver ... Malignancies • Chronic ... #diagnosis #management