3 results
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Dermatomyositis ... /- swelling -> Heliotrope ... Rash - Dysphagia ... #Diagnosis #Pathophysiology ... #Signs #Symptoms
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
• Periorbital heliotrope ... (blue-purple) rash ... • Erythematous rash ... Liver biopsies show ... #dermatology #diagnosis
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Symptoms: • Gottron rash ... papules and Gottron sign ... ) • Shawl sign ... • Heliotrope • ... are elevated < PM