6 results
Dermatomyositis
A middle-aged man describes progressive difficulty combing his hair and rising from a seated position over
Dermatomyositis ... , with: 1) heliotrope ... rash, 2) shawl ... sign, and 3) Gottron's ... Papules #Clinical #Photo
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
• Periorbital heliotrope ... (blue-purple) rash ... • Erythematous rash ... disease and ILD • Liver ... Liver biopsies show
Dermatomyositis with heliotrope rash, shawl sign, and Gottron's papules

A middle-aged man describes progressive difficulty combing his
Dermatomyositis ... with heliotrope ... rash, shawl sign ... rash, 2) shawl ... dermatology #clinical #photo
Dermatomyositis (DM) and Polymyositis (PM): Pathogenesis and clinical findings
Elevated Antinuclear Antibodies: Anti-Jo-1, Anti-OJ, Anti-Mi2, Anti-SRP, Anti-EJ,
Dermatomyositis ... (DM) and Polymyositis ... /- swelling -> Heliotrope ... Rash - Dysphagia ... Pathophysiology #Signs
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
DM with generalized ... to have typical DM ... • Periorbital heliotrope ... (blue-purple) rash ... • Erythematous rash
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Symptoms: • Gottron rash ... papules and Gottron sign ... ) • Shawl sign ... • Heliotrope • ... elevated < PM and DM