13 results
Lactic Acidosis - Differential Diagnosis Framework

Type A: Impaired O2 Delivery (DO2)
 • Decreased O2 Delivery: Hypotension
- Differential Diagnosis ... Shock, Severe Anemia ... Impaired Clearance: Systemic ... liver Failure, ... #Acidosis #Differential
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
Acidosis - Differential ... Diagnosis The ... of Circulatory System ... 30mmHg) - Severe anemia ... #Elevation #Differential
Clinical manifestations of acute liver failure 

Brain: 
Hepatic encephalopathy,  
Cerebral edema,  
Intracranial hypertension,
Clinical manifestations ... Coagulopathy, Lactic ... acidosis Systemic ... suppression, Anemia ... Signs #Symptoms #Diagnosis
Type B Lactic Acidosis
Elevated lactic acid when no systemic hypoperfusion is apparent
Causes:
 • Drugs (metformin, linezolid,
acid when no systemic ... agonist activity • Liver ... to clear) • D-lactate ... Acidosis #causes #differential ... #diagnosis
Thiamine Deficiency - Differential Diagnosis Framework and Clinical Manifestations

Causes of Thiamine Deficiency:
 • Poor intake:
	- Diets
Thiamine Deficiency - Differential ... Diagnosis Framework ... and Clinical Manifestations ... also seen • Lactic ... GFR • Acute liver
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Fever is the main clinical ... with leukopenia, anemia ... thrombocytopenia • Liver ... Triglycerides • ↑ Lactate ... Activation #Syndrome #Diagnosis
Ulcerative Blastomycosis Skin Lesion
57 asymptomatic M from Indiana nonpruritic, painless, progressive skin lesion lower back x
Lives in an old ... Diagnosis? ... Blastomycosis #SkinRash ... #dermatology #clinical ... #photo
Capnocytophaga Canimorsus Skin Rash

40 M presents w/ N, V, severe epigastric pain. SHx: smoker, drinks 18
air conditioning system ... Bandemia, AKI. ... the key to the diagnosis ... initially with a beta-lactam-beta-lactamase ... #photo
Anion Gap Metabolic Acidosis (AGMA) Differential Diagnosis - MUDPILES and GOLDMARK

M - Methanol
U - Uremia
D -
Diagnosis - MUDPILES ... Methanol U - Uremia ... INH, Iron L - Lactic ... D - D-lactate ... and is usually clinically
Cutaneous larva migrans skin Rash
25 F recent Caribbean vacation, walked barefoot on sand and now with
with creepy rash. diagnosis ... Adult hookworms live ... are first-line systemic ... larva #migrans #skinRash ... #photo