191 results
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... Drugs: Direct or ... drugs (e.g. direct ... Prolonged #Causes #diagnosis ... #differential #
Drugs associated with hypokalemia and hypomagnesemia

Hypokalemia
- Shift from extracellular fluid to intracellular fluid compartment
  -
Drugs associated ... Antimicrobials Drug-induced ... panitumumab) #Drugs ... #Medications #differential ... #diagnosis #nephrology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... • Direct renin inhibitor ... • Calcineurin Inhibitors ... #hyperkalemia #differential ... #diagnosis #pathophysiology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Drugs a. ... Drugs a. ... drugs e.g. direct ... Prolonged #Causes #diagnosis ... #differential #
Hyperuricemia - Differential Diagnosis Algorithm
Primary - Over-production
     • Increased turnover of nucleotides
Primary
Hyperuricemia - Differential ... Diagnosis Algorithm ... • ACE inhibitors ... Hyperuricemia #Differential ... #Diagnosis #Algorithm
Drugs causing hyperkalemia
 • Impaired release of renin: NSAIDs, Beta blockers, Cyclosporine, tacrolimus, Diabetes, Elderly
 •
Drugs causing hyperkalemia ... Angiotensin-converting enzyme inhibitors ... Drospirenone #Drugs ... medications #causes #differential ... #diagnosis
Differential Diagnosis of Pleuritic Chest Pain:

Categorized by causes: Cardiac, Pulmonary, MSK, Drug/Toxins, Heme/Onc, Renal, Autoimmune

#Diagnosis #Pleuritic
Differential Diagnosis ... Cardiac, Pulmonary, MSK ... , Drug/Toxins, Heme ... Autoimmune #Diagnosis ... ChestPain #Causes #Differential
Metabolic Acidosis with Anion Gap - KILU Mnemonic

K - Ketoacidosis
	• DKA
		- With normal glucose, ask if
normal glucose, ask ... if on SGLT2 inhibitor ... or leukemia or drug ... Metabolic #Acidosis #diagnosis ... #differential
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
Kidney Injury AKI - Differential ... Diagnosis HEMODYNAMIC ... e.g. calcineurin inhibitors ... #KidneyInjury #Differential ... #Diagnosis #nephrology
Medications causing Acute Kidney Injury (AKI)
Prerenal:
 • Dehydration: Diuretics
 • Altered intrarenal autoregulation: ACEIs / ARBs,
NSAIDs, calcineurin inhibitors ... decongestants) • Any drug ... #Medications #Drugs ... #pharmacology #differential ... #diagnosis